The Confocal Wire Myograph System - 360CW is specially designed to provide very close optical access to the mounted artery or tissue segment, thereby allowing high resolution images of fluorescent dyes or markers by laser scanning confocal microscopy (LSCM). This system elegantly combines LSCM with artery myography to allow simultaneous measurements of isometric force and fluorescence. A perfect example are studies that correlate isometric contractions in an isolated, mounted blood vessel and intracellular Ca²⁺measurements within the vascular smooth muscle cells.